Moderate to severe periodontitis Oral Health
Conditions
Interventions
Participants were randomised into a split-mouth design, with the allocation of the side to be treated (left or right) performed by drawing lots before the initial periodontal examination.
Clinical an
Sponsors
Medical University of Vienna
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Moderate to severe periodontitis with a Periodontal Screening Index of 3 or 4; in regards to new classification: localized or generalized periodontitis of periodontal stage II, III or IV with grades B or C 2. Age 25-55 years 3. Presence of at least one site in each quadrant with probing depths above =5 mm with bleeding on probing 4. Radiologically-detectable alveolar bone loss in all quadrants 5. Good general health
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Intake of antibiotics in the last 6 months 3. Periodontal treatment during the last 6 months 4. Infectious disease, chronic pulmonary disease, immunosuppressive medication or immunodeficiency, cancer, diabetes, other apparent oral infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on probing, assessed during probing with a calibrated standard probe at baseline and 12 weeks after the last treatment (re-evaluation) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Oral hygiene, assessed using the Approximal-Plaque-Index (API) and the Papillary Bleeding Index (PBI) at the initial examination (baseline) and 12 weeks after the last treatment (re-evaluation) 2. Clinical attachment level, measured to the nearest millimeter using a calibrated standard probe at baseline and re-evaluation 3. Periodontal pocket depth, measured to the nearest millimeter using a calibrated standard probe at baseline and re-evaluation | — |
Countries
Austria
Outcome results
None listed