Vertebral morphology in children Musculoskeletal Diseases
Conditions
Interventions
70 healthy growing children (17 girls and 18 boys aged 7 to 8 years, 18 girls aged 11 to 12 years and 17 boys aged 13 to 14 years) will be recruited from schools in Sheffield and Birmingham. Researche
Sheffield Children's Hospital for children from Sheffield schools and Birmingham Children's Hospital for children from Birmingham schools. The receptionists will contact the parents/guardians to arran
Sponsors
Sheffield Children's NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy growing children from school in Sheffield and Birmingham 2. 35 children (17 girls) aged 7 to 8 years, 18 girls aged 11 to 12 years and 17 boys aged 13 to 14 years. Ages have been selected to represent the periods of rapid childhood growth by sex
Exclusion criteria
Exclusion criteria: 1. Ongoing chronic disease 2. Ongoing long-term steroid medication 3. Scoliosis or significant kyphosis 4. History (within preceding 3 years) of road traffic accident 5. History (within preceding 3 years) of back pain/stiffness (particularly morning stiffness) 6. History (within preceding 3 years) of investigation for unexplained fever, malaise, aches/pains 7. Abnormal VFA identified during the study (ACO will review all images to confirm normality. Assent/consent will be obtained from volunteers and parents/guardians to inform the child’s GP should any abnormality be detected, in order for the child to be appropriately referred and investigated)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Participant acceptance of attending hospital, measured using a non-validated questionnaire on Day 1 2. Recruitment rate, defined as the number of participants recruited per month over the 7-month recruitment period | — |
Secondary
| Measure | Time frame |
|---|---|
| Variability of vertebral morphometry in young children measured using analysis of variance for differences in anterior, middle and posterior vertebral heights by age and sex on Day 1 | — |
Countries
England, United Kingdom
Outcome results
None listed