Treatment of lower urinary symptoms in women with trigonitis Urological and Genital Diseases Trigonitis
Conditions
Interventions
Intravesical administration of 40 mg/50 ml solution of sodium hyaluronate (Cystistat) once weekly for 10 weeks and once monthly for 10 months thereafter to all patients.
Sponsors
National and Kapodistrian University of Athens
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women of reproductive age with lower urinary tract symptoms for at least 6 months and trigonitis seen on cystoscopy
Exclusion criteria
Exclusion criteria: 1. Under 18 years 2. Pregnancy or breastfeeding 3. Radiation cystitis 4. Neurogenic bladder 5. Bladder cancer 6. Bladder stones 7. Stress incontinence 8. Urethral diverticulum 9. Pelvic organ prolapse 10. Uterine, vaginal or cervical cancers 11. Endometriosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pain and urgency measured using the visual analogue scale (VAS) at baseline, 10 weeks and 12 months 2. Further symptoms and quality of life measured using the Pain and Urgency/Frequency (PUF) symptom scale at baseline, 10 weeks and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Extent of trigonitis measured using cystoscopy and biopsy at baseline and end of treatment at 12 months | — |
Countries
Greece
Contacts
Public ContactMarios Stavropoulos
Outcome results
None listed