Cardiac surgery ? postoperative atrial fibrillation and pericardial effusion Surgery
Conditions
Interventions
Patients will be randomised to two groups: intervention and control
1. Intervention group: will undergo posterior pericardiotomy in addition to conventional aortic valve replacement
2. Control group
Sponsors
Kuban State Medical University (Russia)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-69 years 2. Informed consent obtained 3. Isolated primary aortic valve replacement
Exclusion criteria
Exclusion criteria: 1. Known history of atrial fibrillation before surgery 2. Amiodarone intake before surgery 3. Known history of thyrotoxicosis 4. Pericardial effusion with a maximum pericardial separation of more than 0.5 cm by transthoracic echocardiography (TTE) before surgery 5. Severe chronic obstructive pulmonary disease (COPD) 6. Left ventricular ejection fraction (LVEF) 50 mm 8. Pericardial adhesions 9. Any active inflammatory disease at the time of surgery (including active infection endocarditis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Mortality 2. The incidence of stroke 3. The incidence of cardiac tamponade Concerned to in-hospital period. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The incidence of atrial fibrillation, measured with 48-h ECG monitoring and then with daily ECG 2. The incidence of pericardial effusion measured by echo twice after removing chest tubes and before discharge 3. The incidence of left pleural effusion measured by echo twice after removing chest tubes and before discharge 4. Length of stay in hospital | — |
Countries
Russian Federation
Outcome results
None listed