Olfactory performance in moderate and severe sleep apnea patients Signs and Symptoms
Conditions
Interventions
Part 1:
Participants attend a study visit at which they undergo several investigations. Firstly, a questionnaire concerning sleepiness and self-estimated quality of the own olfaction h
Sponsors
Cantonal Hospital Aarau
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Outpatients of our department of pulmonary and sleep medicine 2. Age 18 years and over 3. Suffer from daytime sleepiness 4. Show moderate to severe OSA (apnea hypopnea index (AHI) = 15 per hour) in a respiratory sleep study
Exclusion criteria
Exclusion criteria: 1. Lack of written informed consent 2. Insufficient knowledge of the German language 3. Known disease of the nasal cavity or sinuses, or topical nasal therapy usage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Part 1: Self-estimated olfaction is measured using a visual analogue scale (VAS) at baseline and 3 months. Part 2: Self-estimated olfaction is measured using a visual analogue scale (VAS) at baseline and 3 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Part 1: 1. Odor threshold, odor discrimination, odor identification and the summarized value of these three tests threshold, discrimination and identification overall score (TDI) are measured with the aid of a standardized test battery (sniffin’sticks) at baseline and 3 months 2. Daytime sleepiness is measured using the Epworth sleepiness scale (ESS) at baseline and 3 months Part 2: 1. Odor threshold, odor discrimination, odor identification and the summarized value of these three tests threshold, discrimination and identification overall score (TDI) are measured with the aid of a standardized test battery (sniffin’sticks) at baseline and 3 weeks 2. Daytime sleepiness is measured using the Epworth sleepiness scale (ESS) at baseline and 3 weeks | — |
Countries
Switzerland
Outcome results
None listed