Post-TB lung disease Respiratory Post-TB lung disease
Conditions
Sponsors
University of Leicester
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Stage 1 (patient): 1. Aged =18 years 2. Physician diagnosis of COPD Stage 1 (staff): 1. Healthcare staff that would typically refer patients to a clinical PR programme, such as physicians & clinicians. Stage 2: 1. Aged =18 years; 2. Definite diagnosis of a TB-negative patients with PTBLD lung disease 3. Previous TB treatment or finished treatment 4. Medical Research Council dyspnoea score grade 2 or higher
Exclusion criteria
Exclusion criteria: Stage 1 (patients): 1. Unable or unwilling to provide informed consent Stage 2 (staff): 1. Unable or unwilling to provide informed consent Stage 2: 1. Comorbidities such as severe or unstable cardiovascular, other internal diseases and locomotor difficulties that preclude exercise 2. Malignant disease such as lung cancer 3. Evidence of active TB on Chest X-ray or sputum tests within 1 month of assessment 4. Unable or unwilling to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Walking distance (exercise capacity) on the Incremental Shuttle Walk Test (ISWT) at baseline and 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Breathlessness is measured using the Medical Research Council (MRC) dyspneoa scale at 6 weeks 2. Symptom severity is measured using the COPD Assessment Test at 6 weeks 3. Health-related quality of life is measured using the Clinical COPD Questionnaire at 6 weeks 4. Economic impact is measured using the Work Productivity and Activity Impairment questionnaire at 6 weeks 5. Quality of life is measured using the EQ5D-5L questionnaire at 6 weeks 6. Anxiety and depression are measured using the Hospital Anxiety and Depression Scale at 6 weeks 7. Physical activity is measured using accelerometry at 6 weeks 8. Pain is measured using the chest pain questionnaire at 6 weeks 9. Exercise capacity is measured using the Endurance Incremental Shuttle Walk Test at 6 weeks 10. Physical function is measured using the 5x Sit to Stand test at 6 weeks 11. End of study patient focus groups: Participants allocated to the intervention group will be invited to participate in focus group discussions at the end of their Pulmonary Rehabilitation programme to learn about their experience of Pulmonary Rehabilitation. Focus groups will give an insight on views, experiences, opinions and recommendations which will be then helpful to inform design of future PR programmes. We anticipate conducting up to 6 focus groups with 2-10 participants in each. We will invite participants from the intervention group who completed the Pulmonary Rehabilitation programme and who dropped out of Pulmonary Rehabilitation to understand their experiences of the intervention. Focus group discussions will be audio-recorded, each lasting approximately 45-60 minutes, and will be conducted face-to-face by an interviewer and note taker (observer). Focus groups will be transcribed verbatim, with identifiable information removed. 1 | — |
Countries
Kyrgyzstan
Contacts
Public ContactMark Orme
Outcome results
None listed