Testing an online program to help transgender and nonbinary youth cope with gender dysphoria

Trans Care Teen: Adapting an online intervention to reduce symptoms of gender dysphoria for youth

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11106371

Enrollment

346

Registered

2025-11-13

Start date

2026-03-20

Completion date

Unknown

Last updated

2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gender dysphoria and related emotional distress among transgender and nonbinary youth Mental and Behavioural Disorders

Interventions

The Trans Care Teen Intervention (TCTI) is a self-guided, web-based program that includes one introductory module and seven interactive modules completed online over four weeks. The intervention provi

Eligibility

Sex/Gender

All

Age

13 Years to 17 Years

Inclusion criteria

Inclusion criteria: 1. At least 13 and no older than 17 years of age 2. Identify as transgender, transsexual, nonbinary, and/or have a transgender history 3. Experience gender dysphoria 4. Time available to commit to completing a 6–8 hour online intervention within one month and 1-2 hours to complete follow up surveys over 4 months

Exclusion criteria

Exclusion criteria: 1. Under 13 years old 2. Over 17 years old 3. Individual does not identify as transgender, transsexual, nonbinary, and/or have a transgender history 4. Does not experience gender dysphoria 5. Is unable to commit to the time requirements of the study 6. Residing outside of the US 7. Do not have access to an internet connected device, or (8) does not receive guardian consent

Design outcomes

Primary

Measure	Time frame
Gender dysphoria measured using Gender Congruence and Life Satisfaction Scale for Transgender and Gender-Diverse Youth at Baseline, 5 weeks post-registration, and 3 months post-intervention;Gender dysphoria measured using Multidimensional Gender Dysphoria Measure (MGDM) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Mental health distress measured using Depression, Anxiety, and Stress Scale-Youth (DASS-Y) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Gender proximal stressors measured using Gender Minority Stress and Resilience Measure – Adolescent (GMSRM-A) at Baseline, 5 weeks post-registration, and 3 months post-intervention;General coping measured using Coping Scale for Children and Youth (CSCY) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Trans and nonbinary specific coping measured using Trans and Nonbinary Coping Measure (TNCM) at Baseline, 5 weeks post-registration, and 3 months post-intervention	—

Measure

Time frame

Gender dysphoria measured using Gender Congruence and Life Satisfaction Scale for Transgender and Gender-Diverse Youth at Baseline, 5 weeks post-registration, and 3 months post-intervention;Gender dysphoria measured using Multidimensional Gender Dysphoria Measure (MGDM) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Mental health distress measured using Depression, Anxiety, and Stress Scale-Youth (DASS-Y) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Gender proximal stressors measured using Gender Minority Stress and Resilience Measure – Adolescent (GMSRM-A) at Baseline, 5 weeks post-registration, and 3 months post-intervention;General coping measured using Coping Scale for Children and Youth (CSCY) at Baseline, 5 weeks post-registration, and 3 months post-intervention;Trans and nonbinary specific coping measured using Trans and Nonbinary Coping Measure (TNCM) at Baseline, 5 weeks post-registration, and 3 months post-intervention

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Countries

United States of America

Contacts

Public ContactLouis Lindley

llindley2@wisc.edu+1 (0)6082624807

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 23, 2026