Effect of vitamin D supplementation on the functional efficiency of patients after stroke

The effect of vitamin D Supplementation on the fUnctional efficiency of Patients after ischemic strOke undergoing neurological Rehabilitation - a prospective, randomized Trial with a control group (D-SUPORT)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11086312

Enrollment

120

Registered

2023-03-07

Start date

2023-03-01

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who had their first ischemic stroke were admitted to the ward for early post-stroke rehabilitation Circulatory System Stroke, not specified as haemorrhage or infarction

Interventions

Participants in the study will be randomized (using the randomization program from the website random.org) and assigned to one of two comparison groups: group A - a group in which vitamin D supplement

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. First ischemic stroke (time of occurrence 2 weeks before admission to the Department of Neurological Rehabilitation) 2. Stroke confirmed by MR or CT scan 3. Age >18 years old 4. No contraindications to participate in the experiment (consent of the attending physician) 5. No concomitant neurological diseases 6. Written informed consent of the patient to participate in the research

Exclusion criteria

Exclusion criteria: 1. Patients with infection in the last 2 weeks 2. Patients who have taken vitamin D and its derivatives or calcium in the last 3 months 3. Patients with liver and kidney disorders 4. Patients with thyroid dysfunction 5. Patients with aphasia 6. Patients who do not consent to the research

Design outcomes

Primary

Measure	Time frame
1. Clinical symptoms in the course of stroke were assessed using the National Institute of Health Stroke Scale (NIHSS) at baseline and after the intervention and 1 and 3 months after the intervention 2. Everyday activity assessed using the Barthel Scale at baseline and after the intervention and 1 and 3 months after the intervention 3. Degree of disability assessed using the Modified Rankin Scale at baseline and after the intervention and 1 and 3 months after the intervention	—

Measure

Time frame

1. Clinical symptoms in the course of stroke were assessed using the National Institute of Health Stroke Scale (NIHSS) at baseline and after the intervention and 1 and 3 months after the intervention 2. Everyday activity assessed using the Barthel Scale at baseline and after the intervention and 1 and 3 months after the intervention 3. Degree of disability assessed using the Modified Rankin Scale at baseline and after the intervention and 1 and 3 months after the intervention

—

Secondary

Measure	Time frame
Complete blood count, urine analysis, and concentration of 25(OH)D and IGF-1 measured using basic laboratory tests before and after the intervention at baseline and after the intervention and 1 and 3 months after the intervention	—

Countries

Poland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 17, 2026