Anaesthesia Surgery Anaesthesia
Conditions
Interventions
In the first stage of the study, a control group of four patients are subjected to standard anaesthesia monitoring + NIRS and CFM). The anaesthesia is routine anaesthesia based on fentanyl 10 microgra
Sponsors
Uppsala County Council
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Admitted to neonatal intensive care unit 2. Scheduled for major abdominal or thoracic surgery requiring anaesthesia with high dose fentanyl (30 micrograms/kg) 3. Delayed extubation is planned, permitting the use of high dose fentanyl 4. Gestational age 39-44 weeks 5. Aged up to one month old
Exclusion criteria
Exclusion criteria: 1. Extubation planned in the operation theatre 2. Haemodynamic instability requiring inotropic support 3. Weight 44 weeks 5. Treatment with alpha-2-agonist within 12 hours before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of completion of anaesthesia without the addition of rescue anaesthetics (propofol or sevoflurane) and with hemodynamic stability is assessed at the end of the surgery when the patient is handed over to the ICU team. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of adverse events is assessed 24 hours after the end of surgery 2. Postoperative opioid consumption is assessed 24 hours after the end of surgery 3. Postoperative pain is assessed using N-PASS four-hourly until 24 hours after the end of surgery | — |
Countries
Sweden
Outcome results
None listed