The effect of the arm blood pressure cuff inflations during abdominal aortic aneurysm surgery as a measure of protecting kidney and heart from injury

The effect of the arm blood pressure cuff inflations during open abdominal aortic aneurysm surgery as a measure of protecting kidney and heart from injury: a double-blinded, randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11019960

Enrollment

Registered

2010-06-07

Start date

2009-07-01

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm surgery Surgery Aortic aneurysm and dissection

Interventions

Three cycles of upper arm blood pressure cuff inflations 20 mmHg above the baseline, sustained inflation for 5 minutes, deflation for 5 minutes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All patients scheduled for elective or urgent abdominal aneurysm repair 2. Leaking abdominal aneurysm can be taken as long as it is haemodynamically stable

Exclusion criteria

Exclusion criteria: 1. AAA rupture, unstable haemodynamics 2. Kidney Disease - Risk Injury Failure Loss End-Stage Kidney Disease (RIFLE) class failure, needing Renal Replacement Therapy (RRT) 3. Upper limb vascular insufficiency 4. Recent Myocardial infarction, less than two weeks

Design outcomes

Primary

Measure	Time frame
Markers of renal injury 1. Urine Neutrophil Gelatinase Associated Lipocalin (NGAL) 2. Creatinine clearance 3. Serum creatinine levels Outcomes will be measured for three days following surgery	—

Secondary

Measure	Time frame
Markers of cardiac injury: 1. Cardiac troponin 2. Electrocardiography (ECG) changes Outcomes will be measured for three days following surgery	—

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026