The effect of ghrelin on gastric emptying in gastroparesis

Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11016259

Enrollment

Registered

2003-09-12

Start date

2003-02-01

Completion date

Unknown

Last updated

2017-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System: Gastroparesis Digestive System Gastroparesis

Interventions

At time zero infusion will commence with either 5 pmol/kg min ghrelin or saline. This will be blinded to both patient and doctor administering the infusion. Throughout the infusion, euglycaemia will b

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We will recruit 16 patients with type I diabetes mellitus from the Northwick Park Diabetic Cohort who have symptoms compatible with gastroparesis, aged 18-80 years old.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Secondary

Measure	Time frame
Secondary endpoints include: 1. Alleviation of hunger scores 2. Improvement of nausea scores 3. Changes in orocaecal transit	—

Primary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026