Clinical effects of radiofrequency based therapy

Clinical effects of 448 KHz capacitive resistive monopolar radiofrequency (CRMRF) based therapy on patients suffering from chronic osteoarthritis of the knee joint

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10995065

Enrollment

Registered

2015-05-13

Start date

2015-06-15

Completion date

Unknown

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis (OA) of the knee joint Musculoskeletal Diseases Gonarthrosis

Interventions

1. Group A (treatment): CRMRF therapy + current standard treatment twice a week for 4 weeks 2. Group B (placebo): CRMRF therapy + current standard treatment twice a week for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Clinical and radiological diagnosis of OA knee 2. Pain and symptoms in the knee for at least three months 3. Over 18 years of age

Exclusion criteria

Exclusion criteria: 1. Significant underlying medical conditions 2. OA of other joints such as hip or ankle 3. Currently receiving/received (in the last six months) treatment (including invasive procedures) other than standard care 4. Inability to consent

Design outcomes

Primary

Measure	Time frame
Assessed at baseline, immediately after treatment, then again 1 and 3 months following intervention: 1. Visual Analogue Scale (VAS) for pain 2. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for functional quality of life (QoL)	—

Secondary

Measure	Time frame
1. Knee joint range of motion 2. 'Timed up and go' test 3. Skin temperature (physiological) 4. Skin blood flow (physiological) 5. Muscle blood flow (physiological)	—

Countries

United Kingdom

Contacts

Public ContactTim Watson

t.watson@herts.ac.uk+44 (0)1707 284000

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026