Outcomes of two-stage liver resection in the treatment of a rare type of primary liver cancer

Outcomes of modified associating liver partition and portal vein ligation for staged hepatectomy in cholangiocarcinoma

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10972467

Enrollment

Registered

2022-06-16

Start date

2011-10-01

Completion date

Unknown

Last updated

2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholangiocarcinoma Cancer Intrahepatic bile duct carcinoma

Interventions

In 2016, the researchers started using the ALPPS risk score to preoperatively assess patients for the ALPPS procedure. Patients with cholangiocarcinoma relevant hyperbilirubinemia were candidates to u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with cholangiocarcinoma undergoing the ALPPS procedure

Exclusion criteria

Exclusion criteria: Does not meet the inclusion criteria

Design outcomes

Primary

Measure	Time frame
Postoperative morbidities classified as grade I to V based on the Clavien–Dindo classification during the hospital stay	—

Secondary

Measure	Time frame
1. Post-hepatectomy liver failure (PHLF) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period 2. Post-hepatectomy bile leakage (PHBL) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period 3. Post-hepatectomy liver hemorrhage (PHH) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period	—

Measure

Time frame

1. Post-hepatectomy liver failure (PHLF) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period 2. Post-hepatectomy bile leakage (PHBL) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period 3. Post-hepatectomy liver hemorrhage (PHH) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period

—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026