Effect of timing of cord clamping in newborns during first 10 minutes of birth

Effect of timing of cord clamping in the healthy late preterm and term neonate on heart rate during first 10 minutes of birth: A randomized controlled study in a hospital of Nepal

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10944304

Enrollment

1510

Registered

2016-04-05

Start date

2016-04-15

Completion date

Unknown

Last updated

2019-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal heart rate Circulatory System Neonatal heart rate

Interventions

Participants will be randomly assigned to one of two parallel groups in a 1:1 ratio a few minutes before delivery using envelope randomisation. For all women, once they go into labour

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women in active labour coming for delivery in the Maternal Newborn Service Center (MNSC) 2. Normal vaginal delivery 3. Women with no complication during delivery 4. Fetal Heart Rate (FHR=100=160bpm) 5. Women with gestational age (=33 weeks)

Exclusion criteria

Exclusion criteria: 1. Antepartum Stillbirth 2. Intrapartum stillbirth 3. Congenital anomaly 4. Multiple gestation 5. Neonate not breathing at birth

Design outcomes

Primary

Measure	Time frame
Neonatal Heart rate measured using a Moyo’s Fetal Heart Rate Monitor at continuously from the time of birth until 10 minutes of birth and 1, 3 and 5 minute.	—

Secondary

Measure	Time frame
1. Baby’s condition is measured using Apgar score at 1, 5 and 10 minutes 2. Time of establishment of spontaneous breathing is measured in seconds from the time of birth until 10 minutes 3. Neonatal Heart rate measured using a 1, 3, 5 and 10 minutes 4. Neonatal Heart rate measured using Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth 5. Neonatal blood oxygen saturation measured using a Massimo pulse oximeter at 1, 3, 5 and 10 minutes 6. Neonatal blood oxygen saturation measured using a Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth 7. Neonatal pulsatility index measured using a Massimo pulse oximeter at 1, 3, 5 and 10 minutes 8. Neonatal pulsatility index measured using a Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth. 9. Body temperature (10-30 minutes after birth) 10. Respiratory distress at one hour after birth 11. Transcutaneous bilirubin at discharge 12. Baby’s condition at discharge (live/neonatal death)	—

Measure

Time frame

1. Baby’s condition is measured using Apgar score at 1, 5 and 10 minutes 2. Time of establishment of spontaneous breathing is measured in seconds from the time of birth until 10 minutes 3. Neonatal Heart rate measured using a 1, 3, 5 and 10 minutes 4. Neonatal Heart rate measured using Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth 5. Neonatal blood oxygen saturation measured using a Massimo pulse oximeter at 1, 3, 5 and 10 minutes 6. Neonatal blood oxygen saturation measured using a Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth 7. Neonatal pulsatility index measured using a Massimo pulse oximeter at 1, 3, 5 and 10 minutes 8. Neonatal pulsatility index measured using a Massimo pulse oximeter continuously from the time of birth until 10 minutes of birth. 9. Body temperature (10-30 minutes after birth) 10. Respiratory distress at one hour after birth 11. Transcutaneous bilirubin at discharge 12. Baby’s condition at discharge (live/neonatal death)

—

Countries

Nepal

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026