Comparison of how well allopathic and herbal medicine work for the treatment of Entamoeba histolytica

A randomized double blind study to find out whether there is any difference in the efficacy and side effects of Endemali® and a combination of diloxanide furoate and metronidazole

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10942146

Enrollment

202

Registered

2012-07-30

Start date

2008-01-01

Completion date

Unknown

Last updated

2016-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amoebiasis Infections and Infestations Amoebiasis

Interventions

To determine the sample size, we used a <0.05 and power of study as 90%. The effect size considered to be clinically significant, was a 0.15 difference between two groups based on a pilot study. ?Hypo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All the confirmed cases of amoebiasis and between the ages of 5 and 60 years were invited to be included in the study 2. Willing to be assigned to any of the two treatment groups

Exclusion criteria

Exclusion criteria: All those who had multiple problems

Design outcomes

Secondary

Measure	Time frame
1. Side effects 2. Association of age with efficacy 3. Association of sex with efficacy 4. Association of age with side effects 5. Association of sex with side effects Measured at baseline and immediately after completion of course of treatment.	—

Primary

Measure	Time frame
Efficacy at baseline and 5 days after stopping the treatment	—

Countries

Pakistan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026