Indoor air quality and health – the K-HEALTHinAIR project

Knowledge for improving indoor air quality and health - Rotterdam study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN10927320

Enrollment

110

Registered

2023-09-15

Start date

2024-01-07

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General health and well-being in older adults (aged 60+ years) and older adults with pulmonary complaints Respiratory

Interventions

Observational methodology and assessments: 1. Indoor air quality (e.g. particle matter, volatile organic compounds) continuously monitored with air quality sensors 2. Health and well-being (e.g. healt

Eligibility

Sex/Gender

All

Age

60 Years to 110 Years

Inclusion criteria

Inclusion criteria: 1. 60+ years old 2. Cognitively capable of providing informed consent 3. Understand the Dutch language

Exclusion criteria

Exclusion criteria: 1. Not able to comprehend the information provided in Dutch 2. Unable or unwilling to give informed consent 3. Unable to cognitively evaluate the risks and benefits of participation

Design outcomes

Primary

Measure	Time frame
First-year study: 1. Quality of life measured using EQ-5D-5L at baseline, 6-month and 12-month follow-up. 2. Mental health measured using PHQ-9 at baseline, 6-month and 12-month follow-up. 3. Indoor air quality (IAQ)-related health symptoms measured using a diary at months 2, 4, 8 and 10 After the 12-month follow-up, the researchers will assess which measurements will be administered and at what frequency for years 2 and 3 of the study. They will update the registration once they have this information Added 25/11/2025: Follow-up study: 1. Quality of life measured using EQ-5D-5L at baseline, 3- and 6-month follow-up. 2. Mental health measured using PHQ-8 at baseline, 3- and 6-month follow-up. 3. Indoor air quality (IAQ)-related health symptoms measured using a diary at baseline, month 2, 3 and 6	—

Measure

Time frame

First-year study: 1. Quality of life measured using EQ-5D-5L at baseline, 6-month and 12-month follow-up. 2. Mental health measured using PHQ-9 at baseline, 6-month and 12-month follow-up. 3. Indoor air quality (IAQ)-related health symptoms measured using a diary at months 2, 4, 8 and 10 After the 12-month follow-up, the researchers will assess which measurements will be administered and at what frequency for years 2 and 3 of the study. They will update the registration once they have this information Added 25/11/2025: Follow-up study: 1. Quality of life measured using EQ-5D-5L at baseline, 3- and 6-month follow-up. 2. Mental health measured using PHQ-8 at baseline, 3- and 6-month follow-up. 3. Indoor air quality (IAQ)-related health symptoms measured using a diary at baseline, month 2, 3 and 6

—

Secondary

Measure	Time frame
1. Indoor air quality measured with MICA devices that measure IAQ continuously for 36 months 2. Indoor air quality related behavior (e.g. opening windows) assessed using a questionnaire every 6 months 3. Measured using International Consortium for Health Outcomes Measurement (ICHOM) adult and older set (combination) at baseline, 6-month and 12-month follow-up: 3.1. Medication and care use 3.2. Falls 3.3. Lifestyle 4. Living situation (perceived IAQ and outdoor air quality [OAQ], window opening, time spent in scenario) measured at baseline, 6-month and 12-month follow-up 5. Time spent at home measured using a diary at months 2, 4, 8 and 10 After the 12-month follow-up, the researchers will assess which measurements will be administered and at what frequency for years 2 and 3 of the study. They will update the registration once they have this information Added 25/11/2025: Follow-up study: 1. Indoor air quality measured with MICA devices that measure IAQ continuously for 6 months 2. Indoor air quality related behavior (e.g. opening windows) assessed using a questionnaire at baseline, 3 and 6 months 3. Living situation (perceived IAQ and outdoor air quality [OAQ], window opening) measured at baseline, 3- and 6-month follow-up, and the diaries 4. Time spent at home measured using diaries at baseline, month 2, 3 and 6	—

Measure

Time frame

1. Indoor air quality measured with MICA devices that measure IAQ continuously for 36 months 2. Indoor air quality related behavior (e.g. opening windows) assessed using a questionnaire every 6 months 3. Measured using International Consortium for Health Outcomes Measurement (ICHOM) adult and older set (combination) at baseline, 6-month and 12-month follow-up: 3.1. Medication and care use 3.2. Falls 3.3. Lifestyle 4. Living situation (perceived IAQ and outdoor air quality [OAQ], window opening, time spent in scenario) measured at baseline, 6-month and 12-month follow-up 5. Time spent at home measured using a diary at months 2, 4, 8 and 10 After the 12-month follow-up, the researchers will assess which measurements will be administered and at what frequency for years 2 and 3 of the study. They will update the registration once they have this information Added 25/11/2025: Follow-up study: 1. Indoor air quality measured with MICA devices that measure IAQ continuously for 6 months 2. Indoor air quality related behavior (e.g. opening windows) assessed using a questionnaire at baseline, 3 and 6 months 3. Living situation (perceived IAQ and outdoor air quality [OAQ], window opening) measured at baseline, 3- and 6-month follow-up, and the diaries 4. Time spent at home measured using diaries at baseline, month 2, 3 and 6

—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026