Schizophrenia spectrum disorders Mental and Behavioural Disorders Schizophrenia spectrum disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18–65 years 2. Receiving psychosocial rehabilitation 3. Meet International Classification of Diseases–tenth revision (ICD–10) criteria for schizophrenia, schizoaffective disorder, or delusional disorder, as determined by trained Psychiatrists or Clinical Psychologists through clinical interview 4. Clinically stable 5. Treated with a stable dose of the same antipsychotic in the last 6 months 6. Score at least 4 on PANSS delusions or hallucinations, or at least 5 on suspiciousness or persecution, conceptual disorganization, or grandiosity
Exclusion criteria
Exclusion criteria: 1. Concomitant substance abuse 2. Moderate to severe learning disabilities or developmental disorders 3. Non-Spanish-speaking participants 4. Major neurological illness 5. Impaired intellectual functioning (Wechsler Adult Intelligence Scale–IV Full Scale IQ score < 70) 6. Not having the capacity to consent to research participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Metacognitive activity is measured using the Metacognitive Assessment Scale–Abbreviated (MAS-A) at baseline, 16 weeks, and 6 months 2. Social and occupational functioning controlling the influence of the clinical symptoms is measured using the Social and Occupational Functioning Assessment Scale (SOFAS) at baseline, 16 weeks, and 6 months 2. Functioning of patients in four areas independently of symptomatology (socially useful activities, personal and social relationships, self-care, and disturbing and aggressive behaviors) are measured using the Personal and Social Performance Scale (PSP) at baseline, 16 weeks, and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Positive and negative symptoms of schizophrenia are measured using the Positive and Negative Syndrome Scale (PANSS) at baseline, 16 weeks, and 6 months 2. Depressive symtoms are measured using the Beck Depression Inventory–II (BDI-II) at baseline, 16 weeks, and 6 months 3. Anxiety is measured using the Beck Anxiety Inventory (BAI) at baseline, 16 weeks, and 6 months | — |
Countries
Spain