Diarrhoea in adults Digestive System Diarrhoea
Conditions
Interventions
Patients will be randomly allocated to oral rehydration solution (ORS) and bioactive polyphenol solution or ORS and water on day 1 and then monitored for 5 days to determine the time for resolution of
Sponsors
LiveLeaf Inc
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18–80 years 2. Provided informed consent 3. Acute diarrhoea (for 48 hours or less)
Exclusion criteria
Exclusion criteria: 1. History of uncontrolled emesis 2. Signs of coexisting acute sytemic illness (e.g., sepsis or pneumonia) 3. Underlying chronic disease (e.g., heart disease or diabetes) 4. Food allergies or other chronic gastrointestinal diseases 5. Use of probiotic agents in previous 3 weeks 6. Use of antibiotics or anti-diarrhoeal medication in previous 2 weeks 7. Severely malnourished 8. Showed signs of internal bleeding or drug abuse 9. Any condition the physician believed would put the patient at risk if given only standard treatment for diarrhoea 10. Unwilling or unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of diarrhoea, assessed as the time that stool had a Bristol Stool Scale ranking of 4 or less | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in ranking of abdominal pain and bloating between day 1 and day 5 and any adverse events, measured with the Visual Analogue Scale of 0 to 10 | — |
Countries
Nicaragua
Outcome results
None listed