Osteoporosis, residual ridge resorption, quality of the jawbones Musculoskeletal Diseases
Conditions
Interventions
According to the aims of the study the following will be performed:
1. CBCT imaging (Imaging Science’s i-CAT Cone Beam 3-D Dental Imaging System) (this examination will be performed on patients with
Sponsors
Riga Stradins University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: The study will include female patients of Riga Stradinš University Institute of Stomatology who: 1. Undergo CBCT (cone beam computed tomography) diagnostics due to other indications 2. Have menopause 3. Age 55-95 years 4. Agrees to participate in the study 5. At least 5 years edentulous 6. At least 3 years wearing complete dentures 7. Receive prosthetic treatment in Institute of Stomatology (complete dentures)
Exclusion criteria
Exclusion criteria: 1. Patients with diseases and conditions leading to the secondary osteoporosis (kidney disease, hyperparathyroidism, Cushing syndrome, thyrotoxicosis, rheumatoid arthritis, organ transplantation, diabetes mellitus) 2. Women with early menopause (before age 45) or surgical menopause 3. Patients who use or have used a year prior to the study medications affecting bone metabolism (glucocorticoids, bisphosphonates, strontium ranelate, selective oestrogen receptor modulators, HRT, calcitonin, active metabolite of vitamin D, teriparatide, etc.) except those who use calcium less than 1000 mg or vitamin D less than 800 IU per day 4. Smokers 5. Excessive alcohol abusers (more than 14 alcohol units per week)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cone beam computed tomography CBCT imaging analysed using i-CAT Vision and Dolphin Imagining software, OnDemand3DDental, to detect: 1. Volume and density of mandible and maxillae 2. Computed tomography mandibular index (superior), which was the ratio of the inferior cortical width to the distance from the superior margin of the mental foramen to the inferior border of the mandible 3. Computed tomography mandibular index (inferior), which was the ratio of the inferior cortical width to the distance from the inferior margin of the mental foramen to the inferior border of the mandible 4. Computed tomography mental index, which was the inferior cortical width of the mandible 5. Computed tomography cortical index, which was the type of the inferior mandibular cortex (Type 1, 2 and 3) and computed tomography mandibular indexes 6. Cross-section area of the whole mandible, area of the trabecular and cortical bone was measured in region of the mandibular right lateral incisor, first premolar, first molar and second molar All mentioned observations will be performed at the beginning (baseline) of the study. They will not be repeated. | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiological density of first and second cervical vertebra measured using CBCT/OnDemand3DDental software at baseline | — |
Countries
Latvia
Outcome results
None listed