Acute gout Musculoskeletal Diseases Acute gout
Conditions
Interventions
Treatment with 100 mg anakinra daily subcutaneously for three days
Sponsors
University Hospital Complex of Vaud (Centre Hospitalier Universitaire Vaudois [CHUV]) (Switzerland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Acute gout as defined by American College of Rheumatology (ACR) criteria 2. Acute arthritis due to gout which is unresponsive to conventional therapy with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), colchicine or steroids 3. Patients with acute gout who have had side effects or intolerance to either NSAIDs, colchicine or steroids
Exclusion criteria
Exclusion criteria: 1. Patients with on-going or untreated infectious diseases 2. Patients with rheumatoid arthritis, lupus or vasculitis 3. Patients concurrently treated with anti-Tumour Necrotising Factor (TNF) therapies 4. Patients with active cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pain of arthritis 2. Signs of arthritis | — |
Secondary
| Measure | Time frame |
|---|---|
| Biological markers of inflammation | — |
Countries
Switzerland
Outcome results
None listed