Clinical benefits of repeated cerebellar transcranial direct current stimulation sessions in Friedreich ataxia

Clinical benefits assessment of two sessions of 10 days of cerebellar transcranial direct current stimulation (ctDCS) against one ten days session of ctDCS in mitigating Friedreich ataxia cognitive and motor symptoms, a randomised sham controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10844276

Enrollment

Registered

2023-09-07

Start date

2023-09-04

Completion date

Unknown

Last updated

2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Friedreich ataxia Nervous System Diseases

Interventions

This study will test whether two sessions of 10 days of anodal cerebellar transcranial direct current stimulation (ctDCS) given using a brain stimulator, 5 days/week for 2 weeks, 20 min/day, density c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with Friedreich ataxia 2. Aged > 14 to 100 years old

Exclusion criteria

Exclusion criteria: Intolerance to ctDCS

Design outcomes

Secondary

Measure	Time frame
Modification of resting state functional connectivity and brain fingerprints assessed by Magneto-encephalography recordings before and after ctDCS sessions	—

Primary

Measure	Time frame
1. Motor symptoms measured using the Scale for the Assessment and Rating of Ataxia (SARA) before and after each stimulation session 2. Cognitive symptoms measured using the cerebellar cognitive affective syndrome scale (CCAS) before and after each stimulation session	—

Countries

Belgium, Canada

Contacts

Public ContactGilles Naeije

gilles.naeije@hubruxelles.be+3225558196

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026