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Renoprotection with hydration

The effect of preoperative hydration on cardiac surgery-associated acute kidney injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN10684639
Enrollment
110
Registered
2023-11-06
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open-heart surgery in patients with a glomerular filtration rate (GFR) >45 ml/min/1.73 m², not undergoing dialysis, and without ventricular dysfunction Digestive System

Interventions

G-power analysis was used to determine the total sample size and with an effect size of 0.48 (alpha error probability=0.05) and a power value of 0.80, the total required sample size was found to be 11

Sponsors

Kartal Kosuyolu High Specialization Training and Research Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Undergoing an open heart surgery procedure with cardiopulmonary bypass 2. GFR >45 ml/min/1.73 m² 3. Not undergoing dialysis 4. Normal left and right ventricular functions

Exclusion criteria

Exclusion criteria: Patients undergoing emergency surgery, aortic dissection and complex aortic surgery patients, congenital heart surgery patients, minimal invasive and redo patients

Design outcomes

Primary

MeasureTime frame
BUN, creatinine, and GFR values and blood gas values (pH, lactate, HCO3, Na++, K+, etc.) measured on postoperative days 0, 1, 2, 3, and 7, and at the first month and the first year

Secondary

MeasureTime frame
1. Total drainage recorded during the hospital stays of the patients 2. ICU stay recorded during the hospital stays of the patients 3. Total hospital stay recorded during the hospital stays of the patients 4. Extubation times recorded during the hospital stays of the patients

Countries

Turkey

Contacts

Public ContactAyse Zehra;Ayse Zehra Karakoc ;Karakoc

;

aysezehra.karakoc@saglik.gov.tr;aysezehrakarakoc@gmail.com+90 (0)5353927076;+90 (0)5353927076

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026