Influence of Leuconostoc mesenteroides OL3621 on cognitive performance in community-dwelling older adults. Other
Conditions
Interventions
Randomization: computer-generated permuted-block method (block size = 4) to ensure a 1:1 allocation ratio.
Group assignments: double blinded. A trained research assistant was responsible for assignin
taken orally as a 370 mg capsule containing 7 × 10^9 CFU/capsule twice a day: morning and evening)
2. Placebo group: placebo capsules contained equal mass of fulfillment, while probiotic was substitut
Sponsors
Olimp Laboratories Sp. z o.o.
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age between 55 and 85 years 2. Free from diagnosed Alzheimer’s disease (as defined by NINCDS-ADRDA criteria) 3. Free from Parkinson’s disease (according to UK PDS BB criteria) 4. Mini-Mental State Examination (MMSE) score above 24
Exclusion criteria
Exclusion criteria: 1. Clinically confirmed diabetes 2. Active substance abuse 3. Unstable ischemic heart disease 4. Uncontrolled hypertension 5. History of severe allergic reactions, or any other serious medical conditions that, in the investigator’s opinion, might interfere with study procedures or supplement tolerability 6. Use of psychotropic drugs 7. Use of antibiotics and probiotics during the past 3 months 8. Major changes in diet in the last 3 months
Countries
Poland
Contacts
Public ContactAndrzej Malecki
Outcome results
None listed