Efforts to overcome orthostatic hypotension in schizophrenia patients

Effectiveness of leg exercise and hydration interventions on orthostatic hypotension among schizophrenia patients in mental hospital

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10651820

Enrollment

180

Registered

2025-10-16

Start date

2023-11-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient with schizophrenia with experiment orthostatic hypotension Circulatory System

Interventions

Orthostatic hypotension is defined as a significant drop in blood pressure upon standing, specifically a decrease in systolic blood pressure of at least 20 mmHg or diastolic blood pressure of at least

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Diagnosed with schizophrenia 2. Undergoing antipsychotic treatment 3. Identified as having orthostatic hypotension based on blood pressure measurements 4. In a calm, non-aggressive state

Exclusion criteria

Exclusion criteria: 1. Haemoglobin levels <10 g/d l 2. Estimated glomerular filtration rate (e gfr) <30% 3) New York Heart Association (NYHA) class iii or iv heart failure 4. Undergoing dialysis 5. Violent behavior 6. Recent lower limb orthopedics surgery

Design outcomes

Primary

Measure	Time frame
Orthostatic hypotension: blood pressure was measured using a sphymomanometer at 1, 3, 5, and 10 minutes post-standing, daily from day 1 to day 5	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Indonesia

Contacts

Public ContactSari Narulita

sari@binawan.ac.id+62 8128160314

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026