Major depressive disorder Mental and Behavioural Disorders
Conditions
Interventions
Participants are randomised to one of three treatments:
1. Treatment as usual, plus behavioral activation treatment for depression (BATD) in group format weekly for 8 weeks at the premises of the outp
Sponsors
University of Helsinki and Helsinki University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Psychiatric outpatient at the Helsinki University Hospital Department of Psychiatry Mood Disorder Division 2. DSM-5 major depressive disorder 3. Fluency in Finnish 4. Age 18-65 years
Exclusion criteria
Exclusion criteria: 1. Psychotic features 2. Chronic major depressive disorder (uninterrupted duration > 2 years) 3. Principal clinical diagnosis borderline personality disorder 4. Principal clinical diagnosis substance use disorder 5. Imminent threat of suicide 6. Need of psychiatric hospitalization 7. Any illness or symptom hampering participation in the treatments 8. Other ongoing weekly psychotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression score, measured using the Patient Health Questionnaire (PHQ-9) at baseline and after the 8-week intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Response, defined as = 50% decline in PHQ-9 score, measured at 8 weeks 2. Remission, defined as PHQ-9 score < 5, measured at 8 weeks 3. Functional impairment, measured using the Sheehan Disability Scale Score at baseline and 8 weeks 4. Depression score, measured using the PHQ-9 at baseline and 6 months after the intervention | — |
Countries
Finland
Outcome results
None listed