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Study on initial pain management in patients with acute pancreatitis

Multicentre prospective study on initial PAin management IN patients with Acute Pancreatitis: PAINAP study protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN10634411
Enrollment
1000
Registered
2023-05-11
Start date
2022-04-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain management in acute pancreatitis Signs and Symptoms

Interventions

There will be no change in the clinical course for the participants in this trial given this is a observational study. The patients will be followed for 1 month post recruitment to record any complica

Sponsors

Newcastle upon Tyne Hospitals NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years and above 2. First presentation with acute pancreatitis of any etiology

Exclusion criteria

Exclusion criteria: 1. Recurrent acute pancreatitis 2. Chronic pancreatitis 3. Post ERCP pancreatitis (will have been given prophylactic NSAIDs) 4. Those on regular opioids, trycyclic antodipressaants and gabapentinoids for other painful conditions, including chronic pain (for other reasons) 5. Pregnancy

Design outcomes

Primary

MeasureTime frame
Analgesics used during admission (i.e. simple analgesics, mild opioids, strong opioids and epidural analgesia) are measured using patient records at a single timepoint

Secondary

MeasureTime frame
Local and systemic complications of AP measured using patient records at a single timepoint (1 month after admission)

Countries

Argentina, Australia, China, Cyprus, Denmark, Egypt, England, Georgia, Greece, India, Italy, Jordan, Kyrgyzstan, New Zealand, Pakistan, Portugal, Romania, Scotland, Serbia, Singapore, South Africa, Spain, Sri Lanka, Sudan, Türkiye, Ukraine, United Kingdom, United States of America, Wales

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026