Introducing a home-based genomic risk test to screening pathways for abdominal aortic aneurysms

Genomic risk assessment in screening pathways for abdominal aortic aneurysms

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN10623216

Enrollment

Registered

2025-10-21

Start date

2026-02-24

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm population screening Circulatory System

Interventions

This study is a qualitative study split into two distinct work packages. All packages are to be undertaken in the community, coordinated by the University of Leicester. GPs in Leicestershire will be u

Eligibility

Sex/Gender

Male

Age

60 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Men aged 60 – 70 years 2. Able to provide informed consent 3. Speak and understand the English language

Exclusion criteria

Exclusion criteria: Unable to speak or understand the English language

Design outcomes

Primary

Measure	Time frame
1. Public perception and trust of using genomic risk and lifestyle factors as part of an enhanced AAA screening invitation will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 2. Appropriate and publicly acceptable methods for the communication of genomic risk during WP2 will be measured using data collected and documents co-produced during think-aloud testing in WP2 at a focus group and 2 points of structured feedback	—

Measure

Time frame

1. Public perception and trust of using genomic risk and lifestyle factors as part of an enhanced AAA screening invitation will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 2. Appropriate and publicly acceptable methods for the communication of genomic risk during WP2 will be measured using data collected and documents co-produced during think-aloud testing in WP2 at a focus group and 2 points of structured feedback

—

Secondary

Measure	Time frame
W1: 1. Public understanding of genomic risk will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 2. Public perception and trust in using genomic risk and lifestyle factors will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 3. Preferences for communication of genomic and lifestyle risk information will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent W2: 4. Design of an online decision support tool will be measured using data collected and documents co-produced during think-aloud testing in WP2 at a focus group, and 2 points of structured feedback	—

Measure

Time frame

W1: 1. Public understanding of genomic risk will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 2. Public perception and trust in using genomic risk and lifestyle factors will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent 3. Preferences for communication of genomic and lifestyle risk information will be measured using data collected during semi-structured interviews in WP1 at a one-off interview following consent W2: 4. Design of an online decision support tool will be measured using data collected and documents co-produced during think-aloud testing in WP2 at a focus group, and 2 points of structured feedback

—

Countries

England, United Kingdom

Contacts

Public ContactChloe Norman

cgn9@leicester.ac.uk+44 (0)7722192848

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 17, 2026