Vitamin D supplementation and muscle strength in sarcopenic and obese sarcopenic elderly Lebanese people

Effect of vitamin D supplementation on muscle mass and strength in sarcopenic and obese sarcopenic older Lebanese people

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10618249

Enrollment

116

Registered

2017-06-06

Start date

2015-07-02

Completion date

Unknown

Last updated

2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D deficiency Nutritional, Metabolic, Endocrine Vitamin D deficiency

Interventions

Participants are randomised to one of four groups. Those in group one and three have a BMI over 30 and those in groups two and four have a BMI within the normal range. Group 1: Participants receive a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Deficient in vitamin D 2. Age 70 years and over 3. No medical history of type 2 diabetes, congestive heart failure, renal failure or acute heart insufficiency

Exclusion criteria

Exclusion criteria: 1. Not deficient in vitamin D 2. Under 70 years of age 3. Having a medical history of type 2 diabetes, congestive heart failure, renal failure or acute heart insufficiency

Design outcomes

Primary

Measure	Time frame
All primary outcomes are assessed at baseline and after 6 months of intervention. 1. Vitamin D (25(OH)D) is measured by radioimmunoassay (DiaSorin, Stillwater, MN) 2. Handgrip strength is measured in the dominant hand with a Martin vigorimeter (Martin; Elmed, Addison, IL, USA), and the force was expressed in kilograms (kg) 3. Skeletal muscle mass is anticipated from bioimpedance analysis measurements (Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA) and expressed as appendicular skeletal muscle mass (ASMM, kg) 4. Total lean body mass is measured using Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA 5. Fat mass is measured using Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA 6. Parathyroid hormone is measured using a two-site immunoradiometric assay with an NH2-terminal monoclonal antibody as capture (Fitzgerald Industries International Inc., USA)	—

Measure

Time frame

All primary outcomes are assessed at baseline and after 6 months of intervention. 1. Vitamin D (25(OH)D) is measured by radioimmunoassay (DiaSorin, Stillwater, MN) 2. Handgrip strength is measured in the dominant hand with a Martin vigorimeter (Martin; Elmed, Addison, IL, USA), and the force was expressed in kilograms (kg) 3. Skeletal muscle mass is anticipated from bioimpedance analysis measurements (Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA) and expressed as appendicular skeletal muscle mass (ASMM, kg) 4. Total lean body mass is measured using Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA 5. Fat mass is measured using Tanita BC-418 Segmental Body Composition Analyzer, Illinois, USA 6. Parathyroid hormone is measured using a two-site immunoradiometric assay with an NH2-terminal monoclonal antibody as capture (Fitzgerald Industries International Inc., USA)

—

Secondary

Measure	Time frame
All secondary outcomes are assessed at baseline and after 6 months of intervention. 1. Weight (kg) is assessed using the body composition analyzer (Tanita BC-418 Segmental Body Composition Analyzer, Illinois,USA) 2. Body mass index (BMI) is calculated using the standard formula (body weight in kilograms divided by the square of the body height in meters [kg/m²]) 3. Serum creatinine is measured using the Jaffe rate method, the kinetic alkaline picrate (Interpretation and Techniques, Lea and Febiger, Philadelphia)	—

Measure

Time frame

All secondary outcomes are assessed at baseline and after 6 months of intervention. 1. Weight (kg) is assessed using the body composition analyzer (Tanita BC-418 Segmental Body Composition Analyzer, Illinois,USA) 2. Body mass index (BMI) is calculated using the standard formula (body weight in kilograms divided by the square of the body height in meters [kg/m²]) 3. Serum creatinine is measured using the Jaffe rate method, the kinetic alkaline picrate (Interpretation and Techniques, Lea and Febiger, Philadelphia)

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Countries

Lebanon

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026