The dynamic changes and precise classification of parathyroid function within one year after thyroid cancer surgery

The impact of various clinical features on postoperative parathyroid function was analyzed in a cohort of 12,664 patients diagnosed with papillary thyroid cancer who underwent surgical treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN10524966

Enrollment

30000

Registered

2024-09-24

Start date

2023-09-09

Completion date

Unknown

Last updated

2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid carcinoma Cancer

Interventions

In this retrospective cohort study, patients diagnosed with thyroid carcinoma and undergoing surgical treatment at Sun Yat-Sen University Cancer Center (SYSUCC) from 2012 to 2022 were consecutively en

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Confirmed pathological diagnosis of papillary thyroid carcinoma 2. Patients who underwent initial thyroid surgery as primary treatment 3. Normal preoperative parathyroid function (normal PTH and serum calcium level) 4. At least one preoperative and postoperative PTH measurement was conducted

Exclusion criteria

Exclusion criteria: 1. A history of previous thyroid or parathyroid surgery 2. Concurrent parathyroid adenoma diagnosis 3. Other types of thyroid surgeries such as minimally invasive or combined surgeries 4. Lack of complete medical records of patients

Design outcomes

Primary

Measure	Time frame
Postoperative parathyroid hormone values measured using data collected from medical records following standard laboratory testing methods within 30 days postoperatively	—

Secondary

Measure	Time frame
Postoperative parathyroid hormone values measured using data collected from medical records following standard laboratory testing methods from 30 days to 365 days postoperatively.	—

Countries

China

Contacts

Public ContactKang Ning

ningkang@sysucc.org.cn+86 13540679678

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026