Bowel obstruction as a result of colorectal or ovarian cancer Cancer Bowel obstruction as a result of colorectal or ovarian cancer
Conditions
Interventions
At baseline, participants will be provided with a participant information sheet and assessed for eligibility. After signing a consent form the participants will also be weighed and asked about persona
Sponsors
Royal Surrey County Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 14/12/2022: 1. Aged =18 years 2. Able to tolerate the oral diet 3. Diagnosis of colorectal cancer with a primary tumour in situ, locally advanced disease or peritoneal spread causing clinical symptoms of bowel obstruction OR diagnosis of gynaecological cancer with spread to the peritoneum causing clinical symptoms of bowel obstruction 4. Bowel obstruction considered inoperable at the time of consent 5. Presenting with any of the following clinical symptoms of sub-acute bowel obstruction: 5.1. Abdominal pain 5.2. Bloating after eating 5.3. Early satiety 5.4. Nausea 5.5. Vomiting 6. Capacity to give informed consent Previous inclusion criteria: 1. Aged =18 years 2. Able to tolerate the oral diet 3. Confirmed diagnosis of sub-acute bowel obstruction due to underlying malignancy including those with colorectal or gynaecological cancers with a primary or secondary tumour in situ and those undergoing cancer treatment or supportive care 4. Patients diagnosed with advanced inoperable cancers of colorectal or gynaecological origin 5. Presenting in outpatient clinics or admitted from A&E with a minimum of 2 symptoms of the following subacute bowel obstruction: 5.1. Abdominal pain 5.2. Bloating after eating 5.3. Early satiety 5.4. Nausea 5.5. Vomiting 6. Capacity to give informed consent
Exclusion criteria
Exclusion criteria: 1. No symptoms of bowel obstruction 2. Have not already been given the advice to follow the 4 stage bowel obstruction diet 3. Unable to read and communicate in the English language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Acceptability of a 4 stage diet to patients measured using the ease of use questionnaire at 4 weeks 2. Symptoms of sub-acute bowel obstruction (abdominal pain, feeling bloated, feeling full-up quickly, nausea, or vomiting) measured using the Memorial Symptom Assessment Scale questionnaire (MSAS) at baseline and 4 weeks. The MSAS has been adapted to include the key additional symptom of early satiety that can be experienced by patients with sub-acute bowel obstruction and will be graded on a scale of 0 (not at all) to 4 (very much). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. A&E attendances or hospital admissions due to bowel obstruction will be measured from hospital records between 3 months prior to the study and baseline, and between baseline and 4 weeks 2. Health-related Quality of Life measured using the European Organization for Research and Treatment of Cancer Quality of Life questionnaire (QLQ-C30) at baseline and 4 weeks 3. Weight measured in kilograms and as a percentage indicating percentage weight change from start to end of the trial at baseline and 4 weeks | — |
Countries
England, United Kingdom
Outcome results
None listed