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Managing Unusual Sensory Experiences (sometimes called hallucinations), using a new treatment manual, in people who are showing early symptoms that could develop into psychosis

Managing Unusual Sensory Experiences in people with an At Risk Mental States for psychosis (MUSE-ARMS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN10484951
Enrollment
20
Registered
2019-01-17
Start date
2018-12-12
Completion date
Unknown
Last updated
2022-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hallucinations Mental and Behavioural Disorders

Interventions

This study will take a mixed-methods research approach to establish feasibility and acceptability of the MUSE toolkit in a group of service-users with an At-Risk Mental State for Psychosis, using a si
Creswell & Clark, 2011). 20 service-user participants with ARMS will receive assessments on their entrance into the study and after completion of therapist sessions using the toolkit, (which we think

Sponsors

Northumberland, Tyne and Wear NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants will: 1. Be in contact with Early Intervention in Psychosis services and accepted on the ARMs pathways following assessment by the Comprehensive Assessment of At Risk Mental state (CAARMs) 2. Have a history of hallucinations for at least six weeks or a recent history of brief but intense hallucinations. 3. Be aged 16 and above 4. Consider their unusual sensory experiences (voices or visions) as a main presenting difficulty, and indicate that they would like to receive a psychological intervention specifically designed to address hallucinations 5. Have the capacity to provide informed consent 6. Be judged by their clinician to be clinically stable for the preceding 4 weeks

Exclusion criteria

Exclusion criteria: Potential participants will not be eligible if: 1. The experience of hallucinations/psychosis has a strong biological basis (owing to traumatic brain injuries, organic psychoses, or dementia) 2. They have insufficient command of English to complete the research interviews and measures 3. They have an intellectual disability, or severe cognitive dysfunction that might preclude their ability to provide informed consent, understand the study procedure and/or fully appreciate the potential consequences of their participation 4. They have a primary diagnosis of substance misuse dependency 5. They are identified by the care team as being too acutely unwell to participate in the research

Design outcomes

Primary

MeasureTime frame
Psychotic symptoms measured by the Psychotic Symptom Rating Scale (PSYRATS) both before and after the treatment

Secondary

MeasureTime frame
1. Psychotic symptoms measured by the Comprehensive Assessment of At Risk Mental state (CAARMS), perceptual abnormalities and functioning scales only, both before and after the treatment 2. Emotional distress measured by the Depression, Anxiety and Stress Scales (DASS-21) both before and after the treatment 3. Quality of Life measured by the Investigating Choice Experiments Capability Measure for Adults (ICECAP-A) both before and after the treatment 4. Recovery in functioning measured by the Questionnaire about the Process of Recovery (QPR) after the treatment 5. Achieving the service users outcomes from therapy measured by The Choice of Outcome In CBT for psychosEs (CHOICE) both before and after the treatment 6. Acceptability of treatment measured by Satisfaction with Therapy and Therapist Scale (STTS) after the treatment 7. Acceptability of the treatment investigated through structured interviews with both the service user and the clinician after the treatment

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026