Rotator cuff impingement and tears Injury, Occupational Diseases, Poisoning Shoulder injuries
Conditions
Interventions
Subacromial decompression:
Subacromial decompression surgery is performed under general anaesthetic. The procedure involves insertion of the arthroscope into the glenohumeral joint where the joint sur
Sponsors
University of Oxford (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with shoulder impingement syndrome or a partial thickness rotator cuff tear 2. Diagnosis confirmed using ultrasound scan by a trained member of the research team 3. Failed conservative treatment 4. Listed for arthroscopic subacromial decompression 5. Male or female, aged 35 - 75 years old
Exclusion criteria
Exclusion criteria: 1. Full thickness rotator cuff tears 2. Participants with a history of significant trauma (fracture, dislocation/instability, etc.), surgery, osteoarthritis or other significant pathology of the affected shoulder not related to the rotator cuff 3. Patient is unable to consent for themselves 4. No conservative treatment 5. Previous surgery on affected surgery 6. Contraindications to PRP (listed below): 6.1. History of diabetes mellitus 6.2. Platelet abnormality or platelets count less than 100 x 10^9/l 6.3. Haematological disorder 6.4. Serum haemoglobin less than 11 g/dl 6.5. Use of systemic cortisone 6.6. Use of any anticoagulant 6.7. Evidence of gangrene/ulcers or peripheral vascular disease 6.8. History of hepatic or renal impairment or dialysis 6.9. Patient is known to have a psychological, developmental, physical, emotional or social disorder that may interfere with compliance with study requirements 6.10. History of alcohol or drug abuse 6.11. Patient has a religious or cultural conflict with the use of platelet gel treatment or blood products 6.12. Patient has inadequate venous access for blood draw 6.13. Patient is currently receiving or has received radiation or chemotherapy within the last 3 months prior to the study 6.14. Female participants who are pregnant, lactating or planning pregnancy during the course of the study 6.15. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxford Shoulder Score at 6 months post-treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Functional shoulder assessments 2. EQ5D 3. Oxford Satisfaction Index Measured at baseline and 3 weeks, 3 months, 6 months and 12 months post-treatment. | — |
Countries
United Kingdom
Outcome results
None listed