The potential effects of probiotic mouth rinse on halitosis in a sample of dental students

The effectiveness of probiotic mouth rinse in alleviating halitosis clinically and its impact on three strains of bacteria in a sample of dental students

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN10448956

Enrollment

Registered

2025-06-22

Start date

2024-12-22

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis Oral Health

Interventions

Participants will be selected from dental students of the college of dentistry with genuine halitosis and coated tongue. Patients will be instructed to use probiotic mouth rinse two times per day and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Willing to be included in the study 2. Halitosis proven by OLT measure with tongue coating

Exclusion criteria

Exclusion criteria: 1. Those who dislike being part of the study 2. Use of antibiotics in the previous 3 months 3. Systemic illnesses

Design outcomes

Primary

Measure	Time frame
Halitosis determined clinically using organoleptic (OLT) score and tongue coating score [area of tongue coating (Ta), thickness of tongue coating (Tt)] at baseline day 1, 1 and 2 weeks (day 7 and 15) after administration of the mouth rinse	—

Secondary

Measure	Time frame
Strains of bacteria evaluated by examining the whole stimulated saliva using real-time PCR at days 1, 7 and 15	—

Countries

Iraq

Contacts

Public ContactKhadija Ahmed

khadija.ahmad@univsul.edu.iq+964 (0)7701591751

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026