Evaluation of dry eye after 25G pars plana vitrectomy Eye Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consecutive patients over 18 years old who will undergo PPV 25 G by a single surgeon (PM) for Diabetic retinopathy or other causes (i.e. macular hole, epiretinal membrane) 2. Availability to attend Ocular Surface evaluation previous to retinal surgery. 3. Over 18 years old who signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous refractive surgery (LASIK/PRK) 2. Patients under glaucoma medication 3. Contact lens wearers 4. Eye surgery in the last 3 months 5. Patients who require conjunctival opening 6. Active inflammation and Inflammatory and autoimmune conditions (I.E Ocular Cicatricial Pemphigoid, Sjoegren Disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dry eye symptoms were measured using the Ocular Surface Disease Index (OSDI) at baseline, 1 month, and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Tear break-up time and corneal staining (National Eye Institute scale) were assessed at baseline, 1 month and at 3 months 2. Osmolarity (measured in mosm/L) was evaluated at baseline and at 3 months using the TearLab Osmometer 3. Lipid layer thickness (categorized as normal/mild/moderate/severe), non-invasive tear break-up time (measured in seconds), and tear meniscus were assessed at baseline and at 3 months using the Lacrydiag device 4. Evaluation of Conjunctival Impression Citology after small incision Pars Plana Vitrectomy (Nelson Scale and Mucins) at baseline and 3 months after surgery | — |
Countries
Chile