Out of hospital cardiac arrest Circulatory System
Conditions
Interventions
Current interventions as of 10/11/2023:
The aim is to provide data-driven insights to improve outcomes from cardiac arrest.
The objectives are:
1. Provide insights into cardiac arrest
2. Reduce heal
Sponsors
University of Warwick
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 22/01/2019: 1. Adults and children (all ages) 2. Out-of-hospital cardiac arrest 3. Attended by or on behalf of an NHS Ambulance Service 4. Resuscitation attempted Previous inclusion criteria: Patients will be enrolled if after initial screening they fulfil the following criteria: 1. Out of hospital cardiac arrest 2. Resuscitation is attempted (Advanced or Basic Life Support)commenced/ continued by ambulance service
Exclusion criteria
Exclusion criteria: Current participant exclusion criteria as of 10/11/2023: 1. Cardiac arrests during inter-hospital transfer or on acute NHS hospital trust premises 2. Where there is clear evidence of death defined by the Joint Royal College Ambulance Liaison Committee (JRCALC) Recognition of life extinct (ROLE) criteria Previous participant exclusion criteria: 1. Arrest during interhospital transfer or on acute NHS hospital trust premises 2. Patients with clear evidence of death defined by the Joint Royal College Ambulance Liaison Committee (JRCALC) 3. Recognition of life extinct (ROLE) criteria Criteria for ROLE: 3.1. Massive cranial and cerebral destruction 3.2. Hemicorporectomy 3.3. Massive truncal injury incompatible with life (including decapitation) 3.4. Decomposition/putrefaction 3.5. Incineration 3.6. Hypostasis 3.7. Rigor mortis 4. A valid do not attempt resuscitation (DNAR) order or an Advanced Directive (Living Will) that states the wish of the patient not to undergo attempted resuscitation 5. When the patient’s death is expected due to terminal illness 6. Efforts would be futile, as defined by the combination of all three of the following being present: 6.1. More than 15 minutes since the onset of collapse 6.2. No bystander CPR prior to arrival of the ambulance 6.3. Asystole (flat line) for >30 seconds on the ECG monitor screen. Exceptions are drowning, drug overdose/poisoning, trauma 7. Submersion of adults for longer than 1 hour
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Summary data collection: For each case we will collect information from the ambulance clinical record about the time and location of the incident, information about the patient (age, sex, race) the time taken for the ambulance to arrive, the presumed cause of the cardiac arrest, the initial heart rhythm, treatments administered by bystanders and trained ambulance staff. Main outcome measurements: 1. Initial survival (Return of spontaneous circulation i.e. restoring the heartbeat) 2. Medium – long term survival (30 days – 10 year survival). We will obtain this information from the ambulance service (initial survival) and the Medical Research Information Service (MRIS) (medium to long term survival) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The optimal process for case identification and outcome verification following OHCA 2. Factors which influence survival from OHCA in the UK and are feasible to include in risk prediction modelling 3. Feasibility of establishing a national OHCA registry in the UK | — |
Countries
England, United Kingdom
Contacts
Public ContactAdam de Paeztron
Outcome results
None listed