Chronic kidney disease stage 5 on dialysis Urological and Genital Diseases Chronic kidney disease stage 5
Conditions
Interventions
Current interventions as of 22/01/2025:
Patients in the intervention group undergo a baseline assessment followed by a three-week inpatient rehabilitation program tailored to an individualized treat
Sponsors
Bavarian State Office for Health and Food Safety
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis of dialysis-dependent chronic kidney disease 2. Being on the waiting list for a kidney transplant at the Erlangen-Nuremberg Transplant Centre 3. Aged 65 years or older 4. Agrees to participate in the trial and signs the participation
Exclusion criteria
Exclusion criteria: 1. Not listed on the waiting list for a kidney transplant at the Erlangen-Nuremberg Transplant Centre 2. Severe disease or dysfunction that make participation impossible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measure as of 22/01/2025: Body composition measured using InBody 270 and waist circumstance at baseline and after every 6 months until the end. _____ Previous primary outcome measure: Transplantability status (transplantable, not transplantable, pre-waiting list, removed) measured using patient records over the entire duration of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 22/01/2025: 1. Physical performance measured using the sit to stand Test (60), the 6-Minute-Walking-Test, the Berg-Balance-Scale, the frailty scale (Fried) and the timed up and go Test at baseline and after every 6 months until the end. 2. Degree of independence measured by the Barthel Index at baseline and after every 6 months until the end. 4. Nutritional status measured using blood parameters (HbA1c, potassium, calcium, phosphate, vitamin D, parathyroid hormone, erythrocytes, albumin, CRP, CK, ferritin,) at baseline and after every 6 months until the end. 5. Bone health measured using high-resolution peripheral quantitative CT at baseline and after every 12 months until the end. _____ Previous secondary outcome measures: 1. Physical performance measured using the sit to stand Test (60), the 6-Minute-Walking-Test, the Berg-Balance-Scale, the frailty scale (Fried) and the timed up and go Test at baseline, after three weeks and after every 6 months until the end. 2. Body composition measured using InBody 270 and waist circumstance at baseline, after three weeks and after every 6 months until the end. 3. Quality of life measured using Sf-12 at baseline and after every 6 months until the end. 4. Nutritional status measured using blood parameters (HbA1c, cholesterol, LDL, HDL triglycerides, potassium, sodium, chloride, magnesium, gGT, GOT, GPT, AP, calcium, phosphate, vitamin D, parathormone, erythrocytes, reticulocytes, ferritin, total protein, albumin, vitamin B12, folic acid and protein electrophoresis) at baseline and after every 6 months until the end. 5. Bone health measured using high-resolution peripheral quantitative CT at baseline and after every 6 months until the end. | — |
Countries
Germany
Contacts
Public ContactHelge;Judith Krusemark;Kleemann
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Outcome results
None listed