Treatment of pruritus in post-burn patients Skin and Connective Tissue Diseases
Conditions
Interventions
The study was conducted on patients with burns involving >15% total body surface area at the Burn Unit of KBTH. Severe thermal burn was clinically defined as a thermal burn involving >20% TBSA. Select
Sponsors
Ghana College of Physicians and Surgeons
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 16–65 years age (assessments with VAS will be difficult in children and the elderly) 2. Patients with burns involving >15% TBSA (TBSA <15 patients are not admitted for treatment. 3. Patients hospitalised for more than 7 days 4. Patients who are proficient in English, Akan or Ga
Exclusion criteria
Exclusion criteria: 1. Patients who undergo skin grafting involving 5% TBSA were excluded to maintain ‘pure’ cohort 2. Patients with co-morbidities including skin diseases, diabetes, chronic renal diseases, obstructive jaundice, pregnancy, etc. which by themselves caused itching 3. Patients who were septic 4. Patients with impaired cognitive ability 5. Patients with known hypersensitivity reactions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Itch (pain) measured using the visual analogue scale at baseline, day 3, day 7, and day 14 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Insomnia measured using the Athens Insomnia Scale at baseline, day 3, day 7, and day 14 2. Depression measured using the Hospital Anxiety and Depression Scale (HADS) at baseline, day 3, day 7, and day 14 | — |
Countries
Ghana
Outcome results
None listed