Smoking cessation interventions for smokers attending for lung cancer screening (LCS) Cancer
Conditions
Interventions
Current interventions as of 20/03/2026:
The commencement of the smoking cessation intervention (CSCI ) will begin in all treatment groups after the 2-week set-up period post-randomisation.
Once con
Sponsors
University of Nottingham
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: Current key inclusion criteria as of 20/03/2026: 1. Smoked at least one cigarette in the last 7 days at the point of consent 2. 55-75* years of age 3. Able to provide informed consent * The Lung Cancer Screening (LCS) programme offers screening to people up to 74 years and 364 days. The upper age of 75 is used here to allow people to be included in YorQuit if they become 75 between first contact and consent to the YorQuit study. _____ Previous key inclusion criteria: 1. Smoked at least one cigarette in the last 7 days at the point of consent 2. 55-75* years of age 3. Able to provide informed consent * The TLHC programme offers screening to people up to 74 years and 364 days. The upper age of 75 is used here to allow people to be included in YorQuit if they become 75 between first contact and consent to the YorQuit study.
Exclusion criteria
Exclusion criteria: 1. Inability to provide informed consent 2. Previously randomised to YorQuit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 7-day point prevalent carbon monoxide (CO) validated smoking cessation at three months after the CSCI measured using a carbon monoxide breath test at 3 months post-CSCI | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Uptake of stop-smoking support offered measured using self-report questionnaires, app usage data and Smoking Cessation Practitioner (SCP) CRFs at 4 weeks, 3 months and 12 months 2. 7-day point prevalent CO validated and self-reported abstinence from smoking at 4 weeks after the CSCI measured using a carbon monoxide breath test at 4 weeks post-CSCI 3. 7-day point prevalent self-reported abstinence from smoking 3-months after the CSCI measured using a self-reported questionnaire at 3 months post-CSCI 4. 7-day point prevalent CO validated and self-reported abstinence from smoking 12 months after the CSCI measured using self-reported questionnaires and carbon monoxide breath tests and 3- and 12-months post-CSCI 5. Prolonged CO validated and self-reported abstinence from smoking 3- and 12-months postCSCI measured using self-reported questionnaires and carbon monoxide breath tests and 3- and 12-months post-CSCI 6. Acceptability of the intervention delivered in each treatment group measured using qualitative interviews at 4 weeks, 3 months and 12 months 7. Reasons for decline in those not accepting stop smoking support measured using aggregate screening log data at one time point 8. Health-related quality of life measured using self-report questionnaires (EQ-5D-5L) at baseline, 4 weeks, 3 months and 12 months 9. Use of smoking cessation support and other healthcare resources – measured using self-report questionnaire baseline, 4 weeks, 3 months and 12 months | — |
Countries
England, United Kingdom
Contacts
Public ContactLesley Sinclair
Outcome results
None listed