Topic: Gastroenterology, Hepatology
Conditions
Interventions
Electronic home monitoring: Using a tablet PC, patients will carry out a cognitive test and a health enquiry on a daily basis. Based on this treatment for hepatic encephalopathy will be optimised.
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years 2. Patient has capacity and provided written informed consent for participation in the study prior to any study specific procedures 3. Cirrhosis defined either histologically on liver biopsy OR clinically by 2 of: 3.1. Imaging suggestive of cirrhosis (irregular outline and/or spleen >12cm) 3.2. Fibroscan >17.6kPa 3.3. Oesophageal or gastric varices or portal hypertensive gastropathy 3.4. Platelets <120 3.5. Ascites 3.6. Encephalopathy 4. Inpatient at Freeman Hospital, Newcastle or Royal Victoria Infirmary, Newcastle due to overt hepatic encephalopathy (OHE), treated with lactulose
Exclusion criteria
Exclusion criteria: 1. Age 80 2. Unable to provide informed consent 3. Unable to understand written English 4. Malignancy (including HCC) 5. Participating in another interventional study 6. Previous participation in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient acceptability; Timepoint(s): 8 weeks, 16 weeks, 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Admission rates; Timepoint(s): throughout study 2. Completion rate; Timepoint(s): throughout trial 3. Health related quality of life; Timepoint(s): 8 weeks, 16 weeks, 24 weeks 4. Healthcare resource utilisation; Timepoint(s): 8 weeks, 16 weeks 24 weeks 5. Rate of change of therapy; Timepoint(s): throughout study | — |
Countries
United Kingdom
Outcome results
None listed