How does exercise impact bone turnover in people with and without Type 1 diabetes?

The bone metabolic response to exercise in people with and without Type 1 diabetes: an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN10346879

Enrollment

Registered

2019-04-26

Start date

2016-10-01

Completion date

Unknown

Last updated

2021-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 diabetes Nutritional, Metabolic, Endocrine

Interventions

Patients with Type 1 diabetes and a control group of age, fitness, BMI, gender balanced, non-diabetes controls will be recruited. Participants will complete a fixed bout of moderate in

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years old 2. Clinically diagnosed Type 1 diabetes 3. Treated with exogenous insulin (pump or injection) 4. Free from diabetes complications

Exclusion criteria

Exclusion criteria: 1. Type 1 diabetes participants duration of disease less than 1 year 2. Type 1 diabetes HbA1c >10% 3. Musculoskeletal injury

Design outcomes

Primary

Measure	Time frame
Changes in CTX, procollagen type 1 N-Terminal propeptide, and parathyroid hormone from rest, to immediately after exercise. These will be measured by routine biochemical assay.	—

Secondary

Measure	Time frame
Changes in ionised calcium, phospohate, calcium, albumin from rest, to immediately after exercise. These will be measured by routine biochemical assay.	—

Countries

England, United Kingdom

Contacts

Public ContactDaniel West

daniel.west@newcastle.ac.uk0191 2087076

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026