Lung cancer Cancer
Conditions
Interventions
UH-CAN LUNG is a non-randomised feasibility study which will help us to understand if LCS non-responders will perform a self-administered urine home collection kit to provide a viable sample for asses
Sponsors
University Hospital Southampton NHS Foundation Trust
Eligibility
Sex/Gender
All
Age
55 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Invited and twice reminded to participate in the LCS programme. 2. No response received by the LCS team within two weeks of the second reminder to take part (classified as a LCS non-responder). 3. Return of a completed ICF.
Exclusion criteria
Exclusion criteria: 1. Previous enrolment in the LCS programme.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of LCS non-responders will be measured using the number of returned urine samples that are viable for Multi-Cancer Early Detection (MCED) testing | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The total number of urine samples will be measured using study data of the number of returned urine samples over 3ml in volume and within 1 month of posting to the participant 2. LCS assessment booking rate by participants measured using study data (within 1 month of being posted a UH-CAN urine home collection kit) 3. Low-dose CT Scan eligibility in LCS non-responders measured using study data (booked within 1 month of being posted a UH-CAN urine home collection kit) 4. Suspected lung cancer diagnoses in participants returning a consent form who engage with the LCS programme (within 1 month of being posted a UH-CAN urine home collection kit), measured using medical notes 5. Participant satisfaction and choices are measured using the UH-CAN LUNG Study Questionnaire within 1 month of being posted a UH-CAN urine home collection kit 6. The return rate of urine samples within 1 month of being posted a UH-CAN urine home collection kit, stratified by the following variables measured using study data at baseline (single time point): 6.1. IMD quintile 6.2. Quintiles for neighbourhood PM2.5, PM10, NO2, NOx, CO, SO2 and ozone exposure. 6.3. Quintiles for time to nearest hospital 6.4. Age bracket 6.5. Gender | — |
Countries
England, United Kingdom
Contacts
Public ContactVictoria Goss
Outcome results
None listed