Neonatal jaundice in term or late preterm infants in the first week of life. Neonatal Diseases Neonatal jaundice
Conditions
Interventions
Phototherapy by conventional phototherapy device or PEP Bed phototherapy device
Sponsors
KK Research Centre
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Term or late preterm (gestational age 35 weeks or more, birthweight 2000 to 4000 grams) with onset of neonatal jaundice on day 2 to day 7 of life and needing single blue phototherapy.
Exclusion criteria
Exclusion criteria: 1. Infants with jaundice needing double or intense phototherapy 2. Hemolytic Jaundice 3. Blood group incompatibilty 4. Glucose-6-phosphate dehydrogenase deficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of decline in serum bilirubin (SB) level. SB levels were taken up to 12 times hourly until the level was at or below “Off-Phototherapy” level. Rate of decline in SB was measured in each neonate by dividing the difference in levels of SB by hours of phototherapy given to the neonate. For example, case 1 had SB1 (230µmol/L) at the start of phototherapy, SB2 (195µmol/L) after 12 hours (Phototherapy continued) and SB3 (180µmol/L) level was below Off-Phototherapy level. Phototherapy was discontinued after 24 hours. Rate of decline in SB in this case is SB1-SB3 divided by 24 i.e., 230-180 divided by 24 = 2.08µmol/L/hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of phototherapy. The nurses looking after the neonates were asked to feedback on their personal experience on a Likert scale whether they experienced any headache, irritability, giddiness, vertigo, eye glare or nausea. | — |
Countries
Singapore
Outcome results
None listed