Dementia Mental and Behavioural Disorders
Conditions
Interventions
The nursing home residents who are suitable for participation in the study according to the screening and who agree to participate in the study are randomly allocated to intervention and control group
Sponsors
Jiangsu Jicui Aging Research Institute of Technology Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Criteria of the dementia syndrome according to International Classification of Diseases (ICD)-10 2. Mild to moderate dementia: 9 < Mini Mental State Examination (MMSE) score < 24 3. Basic language skills as well as reading and spelling skills (Chinese) 4. Informed consent given
Exclusion criteria
Exclusion criteria: Current participant exclusion criteria as of 17/03/2025: 1. Completely blind or deaf 2. Permanently unable to get out of bed/immobile 3. Did not graduate from elementary school, i.e. less than 6 years in elementary school 4. Unable to communicate (does not respond to simple closed questions) 5. Diagnosis of another disease that causes cognitive impairment: 5.1. Vascular events (e.g. multiple strokes) 5.2. Parkinson’s disease 5.3. Multiple sclerosis 5.4. Severe brain disease (e.g. tumor, injury, hydrocephalus) 5.5. Psychosis (e.g. schizophrenia, mania, bipolar psychosis) 5.6. Severe depression 5.7. Alcohol abuse/drug consumption (addiction) or Korsakoff syndrome 6. Concrete plans/vision to move out of the nursing home Previous participant exclusion criteria: 1. Completely blind or deaf 2. Permanently unable to get out of bed/immobile 3. Did not graduate from elementary school, i.e. less than 6 years in elementary school 4. Unable to communicate (does not respond to simple closed questions) 5. Diagnosis of another disease that causes cognitive impairment: 5.1. Vascular events (e.g. multiple strokes) 5.2. Parkinson’s disease 5.3. Multiple sclerosis 5.4. Severe brain disease (e.g. tumor, injury, hydrocephalus) 5.5. Psychosis (e.g. schizophrenia, mania, bipolar psychosis) 5.6. Depression 5.7. Alcohol abuse/drug consumption (addiction) or Korsakoff syndrome 6. Concrete plans/vision to move out of the nursing home
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition measured by the validated Chinese version of the Addenbrooke's Cognitive Examination-III (ACE-III) at baseline and after 6 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Behavioral and psychological symptoms agitation and aggression measured by the validated Chinese version of the Cohen-Mansfield Agitation Inventory – Short Form (CMAI-SF) at baseline and after 6 and 12 months 2. Activities of daily living measured by the Erlangen Test of Activities of Daily Living – Chinese version (E-ADL-CN) at baseline and after 6 and 12 months (Note: the E-ADL-CN is a newly developed, cultural adapted form of the Erlangen Test of Activities of Daily Living, being validated before the start of the study in people with dementia in Chinese nursing homes) 3. Clinical global impression measured by the two scales Clinical Global impression-severity score (CGI-S) and the Clinical Global impression-improvement (CGI-I) score at baseline and after 6 and 12 months | — |
Countries
China
Contacts
Public ContactElmar;Yu Graessel;Liu
;
Outcome results
None listed