Non-affective psychosis with low positive self-belief Mental and Behavioural Disorders
Conditions
Interventions
Participants will be NHS patients diagnosed with non-affective psychosis, with low positive self-beliefs, and aged 16-30 years old. It is a parallel group randomised controlled trial in which particip
succeeding in challenging situations to develop the belief ‘I can do this’
and engaging in pleasurable activities to develop the belief ‘I can enjoy things’. The achievement and mastery scenario is set in a community garden, with ten tasks relating to the care of plants, ani
Sponsors
University of Oxford
Eligibility
Sex/Gender
All
Age
16 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Participant is willing and able to give informed consent for participation in the trial. 2. Aged between 16 years and 30 years old. 3. Attending NHS mental health services for treatment of psychosis. 4. Primary clinical diagnosis of non-affective psychosis (schizophrenia, schizoaffective disorder, delusional disorder, or psychosis NOS). 5. Low levels of positive self-beliefs indicated by a score of 50 or lower on the Oxford Positive Self Scale (OxPos). 6. Stable medication for at least one month and no planned significant changes at the outset of participation.
Exclusion criteria
Exclusion criteria: 1. A primary diagnosis of another mental health condition (e.g. substance use disorder) that would be the first clinical priority to treat. 2. Current engagement in any other intensive individual psychological therapy. 3. In forensic settings or Psychiatric Intensive Care Unit (PICU). 4. Command of spoken English inadequate for engaging in the VR therapy. 5. Photosensitive epilepsy or significant visual, auditory, or balance impairment that would make use of VR inappropriate. 6. Significant learning difficulties that would prevent the completion of assessments. 7. A participant may also not enter the trial if there is another factor (for example, current active suicidal plans), which, in the judgement of the investigator, would preclude the participant from providing informed consent or from safely engaging with the trial procedures. Reason for exclusion will be recorded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive self-beliefs measured by the Oxford Positive Self Scale [OxPos]. Timepoint(s): baseline, 6 weeks, and 12 weeks. The primary endpoint is 6 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Psychological well-being measured by the Warwick-Edinburgh Wellbeing Scale. Timepoint(s): baseline, 6 weeks, and 12 weeks. 2. Social comparison and negative and positive self-beliefs measured by the Social Comparison Scale, the Brief Core Schema Scale (Negative and Positive Self) and the Everyday Confidence Scale. Timepoint(s): baseline, 6 weeks, and 12 weeks. 3. Depression, hopelessness, and anhedonia measured by the Patient Health Questionnaire-9 (PHQ-9), Beck Hopelessness Scale, Temporal Experience of Pleasure Scale (anticipatory pleasure scale). Timepoint(s): baseline, 6 weeks, and 12 weeks. 4. Anxiety measured by the Generalized Anxiety Disorder Assessment-7 (GAD-7). Timepoint(s): baseline, 6 weeks, and 12 weeks. 5. Paranoia measured by the Revised Green et al Paranoid Thoughts Scale (Revised GPTS). Timepoint(s): baseline, 6 weeks, and 12 weeks. 6. Perceptions of recovery measured by the Questionnaire about the Process of Recovery (QPR). Timepoint(s): baseline, 6 weeks, and 12 weeks. 7. Meaningful activity measured by the Time Budget. Timepoint(s): baseline, 6 weeks, and 12 weeks. 8. Quality of life measured by the EQ-5D and Recovery Quality of Life questionnaire (ReQol). Timepoint(s): baseline, 6 weeks, and 12 weeks. 9. Satisfaction ratings for Phoenix VR measured by the Modified Client Satisfaction Questionnaire (intervention group only). Timepoint(s): 6 weeks. 10. Side effects measured by the Oxford - VR Side Effects Scale (intervention group only). Timepoint(s): 6 weeks. | — |
Countries
England, United Kingdom
Contacts
Public ContactLaina Rosebrock
Outcome results
None listed