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Effects of therapist-monitored high and low dose home exercise program in patients with knee osteoarthritis

Effects of therapist monitored low versus high dose home exercise program in patients with knee osteoarthritis: a randomized controlled trial (Lo-HI dose trial)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN10231069
Enrollment
81
Registered
2026-02-02
Start date
2022-05-02
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis Musculoskeletal Diseases

Interventions

Researchers will compare [hi vs low vs control home exercise program] to see which is more effective in terms of pain intensity, physical function, physical performance, and sleep quality after 8 week
3) single leg standing (SLS) for one set of 10 repetitions
4) semi squat for one set of 10 repetitions
5) seated knee extension exercise for one set of 10 repetitions
6) bilateral hip abduction and adduction exercise, for one set of 10 repetitions
and 7) self-stretching of quadriceps and hamstrings for one set of 10 repetitions. In the high-dose exercise group, participants performed the same exercise program with an increased number of sets (

Sponsors

Dr. D.Y. Patil Vidyapeeth, Pune
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 110 Years

Inclusion criteria

Inclusion criteria: 1. Aged 50 and older 2. Symptomatic knee osteoarthritis diagnosed with grade = 2 OA using the Kellgren-Lawrence severity scale 3. Having knee pain = 2 on a VAS in the past week

Exclusion criteria

Exclusion criteria: 1. Neurological disorders 2. Implanted electrical devices 3. Non-ambulatory status 4. Significant cognitive impairment 5. Systemic inflammatory arthritis (e.g., gout) 6. A history of hip or knee replacement surgery, trauma or surgical arthroscopy of either knee within the last 6 months 7. Prior involvement in a similar study 8. Participation in an exercise program within the last 6 months 9. Intra-articular knee injection within the last 3 months 10. Anticoagulant therapy 11. Recent or imminent surgery (within 3 months), or medical co-morbidities that would preclude participation in exercises

Design outcomes

Primary

MeasureTime frame
1. Pain intensity was measured using a visual analogue scale (VAS) at baseline and week 8 2. Physical function was measured using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) Likert version 3.1 at baseline and week 8

Secondary

MeasureTime frame
1. Physical Performance was measured using the 30-second chair stand test (30sCST) at baseline and week 8 2. Sleep quality was measured using the Insomnia Severity Index (ISI) at baseline and week 8

Countries

India

Contacts

Public ContactMrudula Sangaonkar
mrudula.sangaonkar@dpu.edu.in+91 020-27805888

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026