Cervical cancer screening in younger women

Management of women younger than 30 years in cervical cancer screening: CIN2+ detection rate and referral rate to colposcopy with a screening strategy using HPV testing compared to current practice

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10224660

Enrollment

18000

Registered

2019-12-12

Start date

2018-11-12

Completion date

Unknown

Last updated

2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer screening Cancer

Interventions

Women aged 25 years who come for the first screening round for cervical cancer after invitation within the organised screening programmes in the Piedmont Region will be eligible. No exclusion is plann

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Female 2. Aged 25-28 years 3. Attend the first or second screening round for cervical cancer after invitation within the organised screening programmes in the Piedmont Region

Exclusion criteria

Exclusion criteria: Second round of screening: 1. Previous positive cytological test or previous histologically confirmed CIN2+.

Design outcomes

Primary

Measure	Time frame
The reduced disadvantages of the screening strategy are determined using: 1. Cumulative referral to colposcopy in participants aged 25 to 30 years (including screening at 28 if done). 2. Cumulative detection of CIN2+ in participants aged 25 to 30 years.	—

Secondary

Measure	Time frame
The ability of the screening strategy using HPV testing to select only those under the age of 30 years who need screening up to 30 years is determined using the detection rate of histologically determined CIN2+ at baseline.	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026