Comparing two colonoscopy imaging techniques to detect precancerous changes in patients with inflammatory bowel disease

A prospective randomized controlled study comparing methylene blue dye-based chromoendoscopy versus Fujifilm virtual chromoendoscopy (BLI/LCI) for dysplasia detection in patients with inflammatory bowel disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10174296

Enrollment

300

Registered

2026-03-09

Start date

2023-01-01

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel disease (ulcerative colitis and Crohn’s colitis) Digestive System

Interventions

Randomisation was performed using a computer-generated random sequence with permuted block randomisation (block sizes of 4 and 6, randomly varied). Allocation was concealed using sequentially numbered

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Adults =18 years 2. Confirmed diagnosis of ulcerative colitis or Crohn’s colitis 3. Disease duration =8 years, or any duration with high-risk features (primary sclerosing cholangitis [PSC], extensive colitis, prior dysplasia) 4. Scheduled for elective surveillance colonoscopy 5. Able to provide informed consent

Exclusion criteria

Exclusion criteria: 1. Known colorectal cancer 2. Prior colectomy 3. Severe active colitis requiring urgent intervention 4. Inadequate bowel preparation 5. Pregnancy 6. Inability to provide informed consent

Countries

Kuwait

Contacts

Public ContactYaqoub Alshatti

dralshattiy@gmail.com+965 (0)66635336

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 16, 2026