Mechanical ventilation Respiratory Mechanical ventilation
Conditions
Interventions
A patient was included when readiness to wean criteria were met (see inclusion criteria)
A spontaneous breathing trial (SBT) was then performed, in semi-recumbent patients, on a T-pie
Sponsors
Centre Hospitalier de Lens
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older 2. Under mechanical ventilation for at least 48 hours 3. Satisfied the weaning criteria. The readiness to wean criteria were: 3.1 The resolution or improvement of the underlying cause of respiratory failure for which the patient was intubated 3.2 Hemodynamic stability, defined as heart rate (HR) 90% with fraction of inspired oxygen (FiO2) =0.4 and positive end expiratory-pressure (PEEP) =8 cmH2O, respiratory rate (RR) =35/min, spontaneous tidal volume (Vt) >5 mL/kg, ratio of RR/Vt 13) 3.5 Adequate cough. 4. Patients also had to have an arterial catheter and a central line with the tip confirmed by x-ray to be in the superior vena cava near at the entrance or in the right atrium.
Exclusion criteria
Exclusion criteria: 1. Tracheotomized patients 2. Do-not-reintubate orders 3. Pregnancy 4. No informed consent 5. Poor cardiac echogenicity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weaning failure rate from mechanical ventilation defined as the development of at least one of the following: 1. Respiratory acidosis with pH 45 mmHg 2. Arterial oxygen saturation 0.5 3. RR>35/min 4. Clinical signs of respiratory fatigue | — |
Countries
France
Outcome results
None listed