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Intolerance of uncertainty in children with autism spectrum disorder: a feasibility trial

Addressing intolerance of uncertainty in children with autism spectrum disorder: an intervention feasibility trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN10139240
Enrollment
60
Registered
2018-05-14
Start date
2018-05-15
Completion date
Unknown
Last updated
2022-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism spectrum disorder Mental and Behavioural Disorders Childhood autism

Interventions

Sixty parents of children with ASD and anxiety are recruited from NHS services. Randomisation will occur through the online service ‘Sealed Envelope’ (https://www.sealedenvelope.com/). Families will b

Sponsors

Northumberland, Tyne and Wear NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Parents of autistic children who: 1.1. Are aged 6-16 years 1.2. Experience some anxiety 1.3. Do not have intellectual disability OR have mild to moderate intellectual disability 1.4. Have sufficient language ability to complete appropriate outcome measures (with assistance if required) 2. Parents/carers have sufficient spoken and written English to provide written informed consent, complete assessments and participate in the intervention

Exclusion criteria

Exclusion criteria: 1. Children who experience severe and complex anxiety disorder 2. Children with severe intellectual disability 3. Children with complex health conditions 4. Parents with significant mental health difficulties

Design outcomes

Primary

MeasureTime frame
Intolerance of uncertainty is measured using target behaviour rating of target situations at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment

Secondary

MeasureTime frame
1. Children’s intolerance of uncertainty (parent and child reported) is measured using the Intolerance of Uncertainty Scale (IUS – P &C, Walker, 2009) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 2. Children’s anxiety is measured using the Screen for Child Anxiety Related Emotional Disorders (SCARED; Birmaher et al., 1997) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 3. Children’s anxiety (parent and child reported) is measured using the Anxiety Scale for Children - ASD (ASC-ASD, Rodgers et al., 2016) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 4. Children’s activities and participation are measured using the Children’s Assessment of Participation and Enjoyment (CAPE, King et al., 2004) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 5. Parents’ self-efficacy is measured using the Parent Self-efficacy scale (Sofronoff & Farbotko, 2002) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 6. Parents’ own intolerance of uncertainty is measured using the Intolerance of Uncertainty Scale (IUS-12; Carleton, 2012) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 7. Parents’ mental wellbeing is measured using the Depression, Anxiety and Stress Scale (DASS, Lovibond & Lovibond, 1995) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment 8. Treatment expectancy is measured using the Credibility/Expectancy Questionnaire (Devilly & Borkovec, 2000) at baseline, immediately post treatment (or equivalent for Understanding Autism), 12 weeks and 26 weeks post treatment

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 2, 2026