Oral lichen planus Oral Health Lichen planus
Conditions
Interventions
30 patients with oral lichen planus were included in the study. After clinical diagnosis and histopathological confirmation, the selected patients were divided into two groups – group A and group B, t
Sponsors
D.Y. Patil University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with oral lichen planus 2. Age range 18 to 70 years
Exclusion criteria
Exclusion criteria: 1. Patients with a history of malignancy, immunocompromised diseases, metabolic diseases, pregnancy or breastfeeding, systemic viral infections, other red and white lesions 2. Undergoing systemic therapy that may interfere with disease prognosis 3. Active therapy for oral lichen planus 4. Known allergies to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of the lesion measured using self-modified Thongprasom sign scoring system for oral lichen planus, at baseline (day 0) and days 15, 30 and 45 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pain intensity measured using the visual analogue score (VAS) at baseline (day 0) and days 15, 30 and 45 2. Clinical erythema measured using Clinician Erythema Assessment grading scale at baseline (day 0) and days 15, 30 and 45 2. Incidence of adverse drug reactions (if reported) during the treatment course 3. Quality of life assessed using the Chronic Oral Mucosal disease questionnaire (COMDQ) after treatment completion | — |
Countries
India
Outcome results
None listed